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Although the role of NKCC2 in renal handling of glucose remains poorly defined, NKCC2A KO mice developed several aspects of MetS including increased basal glycemia, glucose intolerance and insulin resistance (Kelly et al., 2019), but not hypertension, at least when mice were young (Oppermann et al., 2007)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Sohn SJ, Barrett K, Van Abbema A, Chang C, Kohli PB, Kanda H, et al

From the above findings, it was clarified that administration of the Si-based agent significantly relieved damage to the large intestine by suppressing the progression of inflammation

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This review generally overviews the relationship between COVID-19 and PD (Fig