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Both procedures produce rapid weight loss but require careful nutritional management forever after

4 , 62 , 63 Longterm NMN treatment also significantly reduced the proportions of apoptotic signals and markers of aging in the ovaries of aged mice

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Moreover, it downregulated oxidative stress-related pro-inflammatory proteins, such as p38 MAPK and NF-B, and decreased the Bax/Bcl-2 ratio, thus reducing apoptosis and enhancing mucosal cell survival

GLP-1 ((glucagon-like peptide-1) drugs such as semaglutide work by mimicking a natural hormone that signals the brain to feel full and slows down digestion, helping one eat less and lose weight more effectively

Matheus Meneguzzi Brambilla , nutricionista pela USP, com especializao em nutrio esportiva pela Unesp (Universidade Estadual Paulista).