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Early clinical trials suggest it may represent a groundbreaking advancement in obesity and diabetes treatment

The relevant study also found that the 1-year average weight loss of participants (LIR 3.0 mg) was 9.2 kg reporting nausea/vomiting episodes, while that of participants without nausea/vomiting was 6.3 kg

You have a smaller appetite, and you dont feel hungry, leading to weight loss

Conversely, bile acids impact the bacterial composition of the microbiota by exhibiting strong antimicrobial functions (203)

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Future studies should incorporate human iPS cell-derived astrocyte models, precision delivery platforms and multimodal biomarkers to bridge these gaps and accelerate astrocyte-based therapies from mechanistic insight to clinical practice