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Reductions in morbidity and mortality with steroidal MRA use among individuals with HF with reduced ejection fraction have led to these agents being included as cornerstones of medical therapy for HF [61]

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When you inject early, you are adding a new dose on top of a higher-than-usual residual level

The change from baseline and the differences in the change from baseline between treatments were based on the Least Square Means from this model