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As compared to liraglutide and exenatide, semaglutide has longer half lifetime owing to its higher albumin binding and longer fatty acids in its structure, in addition to possessing higher potency to GLP-1R (Knudsen and Lau 2019)

1 Learning from the past to promote present and future healthy trajectories Over the past decades, a wealth of findings rekindled the interest in the older concept of Epigenetics (Above the genome), which was coined by Conrad Waddington to explain how identical genotypes could unfold different phenotypes as development proceeds [7, 8]

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