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Most people begin noticing reduced appetite within the first 1-2 weeks of starting semaglutide

Factors include starting weight, baseline metabolic health, consistency of medication use, dietary habits, physical activity, genetic factors, medical history, and other individual variables

Adam lost 91 lbs

CONCLUSIONS CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported

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Tirzepatide (Zepbound) was another drug assessed in a study conducted in New England Journal of Medicine for weight loss in individuals with obesity