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J Physiol Paris 94:99104 Sikiric P, Jelovac N, Jelovac-Gjeldum A et al (2001) Anxiolytic effect of BPC-157, a gastric pentadecapeptide: shock probe/burying test and light/dark test

In (C) and (D), peroxide and Wat3 are present between CuA and CuB

Activation of the CHOP-ERO1-IP3R1-CaMKII pathway induces membrane-bound nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase) subunit 2 (NOX2), resulting in ROS production (Tabas and Ron, 2011)