The MRSD can be further refined based on the anticipated therapeutic window : the dosage range sitting between the minimum effective concentration (MEC) and the minimum toxic concentration (MTC)
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Danicke S, Heymann AK, Oster M, Wimmers K, Tesch T, Bannert E, et al
Nature (2020)
Nuclear receptor coactivator 4 (NCOA4) mediates ferritin degradation, causing iron release, and heme oxygenase-1 (HO-1) can catalyze the degradation of heme to produce iron to LIP [40]
The town of Naranjo de Chila is a dusty mountain pueblo in southwestern Michoacn, a lifetime from the high-rises of Guadalajara