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MiRNAs such as miR-526b and miR-578 regulate the expression of RAAS components, which not only exacerbate hypertension but may also influence tumor cell drug resistance and invasiveness, thereby further promoting the progression of lung cancer [91,92,93,94]

(21) This aligns with the mechanostat theory, which posits that bone adapts to changes in mechanical forces by modulating turnover rates

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In view of the fact that SLC38A2 and SLC1A4 compete for alanine in pancreatic cancer, we speculated whether SLC38A2, which is highly expressed in DCs, also has a similar phenomenon in the immune microenvironment to meet its function