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Spinal cord injury For many decades, since the 1940s, based purely on correlative observations, reactive astrocytes that surround tissue lesions after traumatic injuries or stroke were regarded as glial scars that were the primary cause for the failure of axon regeneration and functional recovery after spinal cord injury (SCI) and other causes of axotomy in the CNS

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Furthermore, comparing Prdx Km for H 2 O 2 with that of GPx and catalase exceeding even the millimolar range [180] suggests that the role of Prdx is rather as a sensor of H 2 O 2 [178] than oxidative stress condition reversal