Betulin, used as a positive control, has a similar effect on inhibiting SREBP2 maturation as the combined treatment of metformin and simvastatin (Fig
Inflammation is a natural response to injury or excessive exercise but too much inflammation can cause significant pain
GLP-1 drugs like Ozempic and Wegovy, for example, have transformed the treatment of diabetes and obesity
The importance of fatty acid oxidation for the survival of cancer cells in many forms of cancer is becoming more apparent
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The extracted data were also organized into a structured summary table including model type, species, organelle interaction studied, and the main mitochondrial phenotype, to facilitate comparison across the heterogeneous body of experimental evidence