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Additionally, tirzepatide may cause fewer gastrointestinal side effects and provides extra benefits for patients with type 2 diabetes or increased cardiovascular risk, including improved glucose control and reduced cardiovascular event risk

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Certain foods are particularly notorious for affecting urine smell: Asparagus contains asparagusic acid, which breaks down into sulfur-containing compounds Coffee and caffeinated beverages can impart a distinctive odor and have mild diuretic effects Garlic and onions contain sulfur compounds that are excreted in urine Riboflavin (vitamin B2) supplements can cause bright yellow urine Patients should be aware that severe gastrointestinal symptoms can lead to acute kidney injury, as noted in FDA warnings

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While minor side effects such as nausea affect many people, most do not find them problematic enough to stop treatment

A combination of hydration, saliva-stimulating products, and protective oral care products provides the most complete relief