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After 12 treatment sessions, patients were assessed for pain intensity, knee flexion range of motion, a timed up-and-go test, a 6-min walk test, and knee functionality compared to pre-treatment baseline measurements

That study revealed that the accumulation of GSH in response to -ionone coincided with increased gene expression of GR and the GSH biosynthesis enzymes -glutamylcysteine synthetase and glutathione synthetase relative to untreated broccoli

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In the intervention group, serum levels of AST and ALT decreased significantly at the end of study

Furthermore, our findings highlight the importance of using standardized techniques in preclinical and clinical research, particularly in the case of REDOX biology as shown here