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The Food and Drug Administration has approved the second GLP-1 pill to treat obesity, this time from drugmaker Eli Lilly

NUMB dysfunction defines a novel mechanism underlying hyperuricemia and gout

It is produced naturally in the body, primarily in the liver, and is vital for numerous cellular processes

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These mechanisms relevant for musculoskeletal repair where cell recruitment and organization critical

Typically, it presents as a pigmented longitudinal band (LM), but it can on rare occasions affect the entire nail plate (total melanonychia).17,21,22 Surface and free-edge nail plate dermoscopy may be used to assist in the differential diagnosis of LM