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Clinical trial results show that semaglutide users experienced constipation for a median of 47 days

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"There's nothing in the current evidence that raises unique safety red flags" beyond the known GLP-1 side effects and risks, says Srivastava

doi: 10.1053/j.gastro.2011.02.018 7 KnudsenLBLauJ

Semaglutide mimics a protein in your body called GLP-1, and activates GLP-1 receptors in your body to increase the production of insulin, a hormone that helps escort glucose into your cells where its used for energy, Dr