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Behavioral Neuroscience , 52(1), 123-140

Significance during GLP-1 therapy: Hyponatremia (low sodium levels) can occur during GLP-1 therapy due to increased fluid loss or dilutional effects

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Ignoring reconstitution dates leads to using degraded product

Increased circulating levels of proinflammatory cytokinesTNF-alpha, IL-1 beta, and IL-6notably impair insulin secretion and promote pancreatic beta-cell apoptosis in patients with type 2 diabetes [34]

Injection-site reactions: Mild redness, swelling or discomfort that typically resolves quickly