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Female Balb/c mice (8 weeks, Animal Resources Centre, Perth, WA, Australia) were housed at 20 2C and maintained on a 12 h light, 12 h dark cycle (lights on at 06:00 h) with ad libitum access to standard rodent chow and water

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doi: 10.1172/JCI112855 [DOI] [PMC free article] [PubMed] [Google Scholar] 91

Consequently, discontinuation of oral semaglutide often leads to weight regain