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Urolithin A , a gut metabolite from pomegranate and berries sold as a mitophagy activator, has human trials showing improved muscle strength and mitochondrial markers in older adults, but the evidence is for muscle and metabolism, not the brain

[DOI] [PubMed] [Google Scholar] 92.James SJ, Cutler P, Melnyk S, et al

Imaizumi T

MOTS-c is real biology : It is encoded within mitochondrial DNA and has been shown in laboratory studies to influence metabolic pathways such as AMPK signaling, which is involved in energy balance and insulin sensitivity