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The middle shelf is usually best

A recent analysis found that semaglutide and tirzepatide, at the current list prices, were the least cost-effective weight loss medications, when compared to naltrexone/bupropion (Contrave) and phentermine/topiramate

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The biggest benefit of Mounjaro is that it seems to work well for patients with diabetes, and it triggers major weight loss for patients

If you have thyroid nodules or thyroid-related concerns, discuss the risk-benefit profile with your endocrinologist before starting either medication