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As a result, rather than being a direct inhibitor of thyroid gland function, it acts as a peripheral antagonist of thyroid hormone action (186)

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Yield: 20%, purple solid, 1 H NMR (500 MHz, CDCl 3 ) 8.51 (s, 1H), 8.17 (d, J = 7.8 Hz, 1H), 7.54 (s, 1H), 7.247.06 (m, 11H), 7.036.91 (m, 4H), 6.86 (d, J = 8.9 Hz, 2H), 6.616.51 (m, 3H), 4.133.99 (m, 2H), 3.933.82 (m, 1H), 3.753.67 (m, 1H), 3.563.47 (m, 2H), 3.453.40 (m, 2H), 3.353.23 (m, 1H), 3.213.14 (m, 2H), 3.142.98 (m, 10H), 2.362.19 (m, 2H), 1.751.57 (m, 4H), 1.551.38 (m, 10H), 1.381.20 (m, 4H) ppm

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Therefore, the SFN effects on T-cell functions can at least partly be explained by depletion of GSH and accumulation of oxidized proteins

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