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Clinicians and patients may consider this risk before initiating this GLP-1R agonist in those with a history of NAION, monocular patients and those with low vision at baseline, the researchers wrote in their abstract

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The latter, while providing valuable real-world signals, are inherently susceptible to confounding by indication and selection bias, as patient characteristics and co-morbidities may differ significantly between treatment groups

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Ho JY, Kraemer WJ, Volek JS, Fragala MS, Thomas GA, Dunn-Lewis C, Coday M, Hakkinen K, Maresh CM