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resolve with titration.[1][43] Absolute Contraindications : History of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2.[3][44] Relative Contraindications : Pancreatitis, severe GI disease, pregnancy/breastfeeding.[1][45] Monitoring Parameters : HbA1c, lipids, liver enzymes, renal function every 3 months.[4][46] Regulatory Status FDA Classification : Investigational (Phase 3)

Comprehensive labs should guide the decision before any medication is started

Singh AP (2021) Genomic techniques used to investigate the human gut microbiota

During the early weeks of treatment, this dose may begin to influence appetite signals, helping some patients feel fuller sooner and reducing the frequency of food cravings

Lee JM, Sharifi M, Oshman L, Griauzde DH, Chua K-P