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That warning followed increasing scrutiny of the drugs safety profile

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A research study to see how semaglutide works compared to placebo in people with type 2 diabetes and chronic kidney disease (FLOW) Accessed 22 Mar 2021

These findings indicate that GLP-1RAs have anti-adhesive and anti-thrombotic properties in the endothelium that may delay the development of atherosclerosis [110]

It should be noted that the steps mentioned above are the main steps in the synthesis of Semaglutide, and the actual synthesis may involve more intermediate steps and adjustments