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[53] studied the potential role of inflammatory, metabolic, liver damage, and iron metabolism mediators on the inverse association between HCC risk and coffee consumption, as suggested by the reduction in IL-6 levels, a biomarker of inflammation and innate immunity, together with reduced hepatocellular and cholestatic damage biomarkers, i.e., GLDH (glutamate dehydrogenase), ALT (alanine aminotransferase), AST (aspartate aminotransferase), GGT (-glutamyl transferase), and bilirubin
Collectively, these data suggest that reversing or attenuating oxidative stress and mitochondrial dysfunction could potentially increase lifespan
Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications
According to the Mayo Clinic, vegetarians, vegans, individuals with digestive tract conditions that affect the absorption of B12, and the elderly are at an increased risk of B12 deficiency [8]
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