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Addressing these gaps requires integrative approaches combining high-resolution imaging, omics technologies, and advanced infection models to delineate pathogen-specific and conserved mechanisms of mitochondrial manipulation

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In addition to the canonical CoQ biosynthetic enzymes, recent studies have revealed that reticulon 4-interacting protein 1 (RTN4IP1), a mitochondrial matrix protein, participates in CoQ 9 biosynthesis by regulating the activity of COQ3 34

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Interaction network of ALT-related proteins, pan-cancer oncogenes, and metabolites

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