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Among available RCTs, only hematologic outcomes were assessed: no evidence exists to confirm the assumption that hematologic outcomes gained with adjuvant therapy share the same risk-benefit profile as those gained with ESA and iron therapy alone

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24 Similarly, the AngioSafe Type 2 Diabetes study, in a case-control analysis of 3,154 patients with type 2 diabetes, found that GLP-1RA use was not associated with severe DR, although HbA 1c among other covariates such as diabetes durationwas

was supported by the project no.143233, which has been implemented with the support provided by the Ministry of Culture and Innovation of Hungary from the National Research, Development and Innovation Fund, financed under the FK_22 funding scheme

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This example underscores a broader point: not all underexplored peptides need to become drugs to influence drug discovery