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Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults

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Acknowledgements The National Natural Science Foundation of China (82073144, J.W.), the Health Commission of Zhejiang Province (JBZX-202004, J.W.), the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China (LHDMD22H310005, J.W.)

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While antibiotics serve important medical purposes, supporting your microbiome during and after treatment helps minimize side effects and accelerate recovery

The space was thoughtfully designed to inspire collaboration, drive success, and foster a sense of connection both within our teams and within the community. As part of its ongoing support for Texas communities, Wells Fargo also announced today a $1 million donation to OneStar Foundation for the Central Texas Flood Recovery Fund to further help communities across Texas Hill Country rebuild, bringing the companys year-to-date total donations towards flood relief and recovery efforts across the state to $2 million