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If a prescriber determines the benefit justifies the risk in a specific case, the lowest available dose (0.5 mg) should be used no more than twice weekly, with biweekly copper monitoring and a predefined stopping rule

The American Diabetes Association recommends individualized nutrition therapy rather than a one-size-fits-all approach

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It is not a recognised scientific name, a standardised formulation or an authorised medicine

Many people with low B12 feel fatigued and sluggish

All therapies were given once weekly, but the study adopted a flexible protocol that allowed patients to alter their dosing throughout the trial