GLP-1 receptor agonists are not recommended in patients with a family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2A or 2B, due to an association between GLP-1 receptor agonists and benign and malignant thyroid C cell tumors in rodents [49]
however, in participants undergoing heavy physical stress (e.g., marathon runners, skiers, or soldiers in subarctic conditions), vitamin C supplementation halved the incidence of colds (5 trials)
Nauck et al., 2016
Rybelsus and Trulicity are both FDA-approved GLP-1 receptor agonists that help regulate blood sugar levels in patients with type 2 diabetes, but they differ significantly in administration: Rybelsus is the first oral semaglutide (taken as a daily pill), while Trulicity (dulaglutide) requires a weekly injection
Side Effects: Common side effects include nausea, vomiting, diarrhea, and constipation
Intranasal peptide administration has become an increasingly valuable area of pharmaceutical research because it offers a practical model for evaluating peptide transport and formulation performance
