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Peripheral vascular disease and diabetes

The accumulation of fat can lead to a dysfunction in the biosynthesis of L-carnitine (Figure 1) in the liver thus inducing a negative feedback loop, whereby less L-carnitine is produced which leads to enhanced impairment of fatty acid oxidation re-enforcing fatty liver disease

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Food Res Int 140:109905

Safety in the ICH population is not fully established, and current international guidelines do not endorse statins as standard therapy for ICH 51 (Fig