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tirzepatide pregnancy

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Description

In the pivotal clinical trials that led to FDA approvalincluding the SUSTAIN trials for diabetes management and the STEP trials for weight managementmusculoskeletal symptoms including joint pain were reported, but at rates generally comparable to placebo groups

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Endocrine 55(3):712731

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1 GLP-1RAs can be added to any combination of other therapies (except DPP-4 inhibitors), including insulin and SGLT-2 inhibitors, although this is not subsidised by the PBS

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In a sensitivity analysis, we re-estimated the propensity score-weighted models with additional adjustment for maternal pre-pregnancy BMI, maternal age and pre-existing diabetes

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Semaglutide is now in phase 3 clinical trials

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Calm your system

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