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Luedde T, Schwabe RF (2011) NF-B in the liverlinking injury, fibrosis and hepatocellular carcinoma

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These changes occurred before the increase in THDA levels, indicating that the loss of BDNF-TrkB signalling and upregulation of GSTO2 happens before the hyperdopaminergic state, as with the Trkb Penk -KO mice, supporting that GSTO2 increase is more likely a cause of neurodegeneration than a consequence of it