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By converting O 2 to OH- in the presence of Fenton reactive metals, SOD can also generate a more reactive and destructive ROS, hydroxyl radical (OH )

Next steps in clinical translation First-in-human safety trials (phase I) are essential: to assess dose tolerability, pharmacokinetics, biodistribution, peptide half-life, clearance, immunogenicity

High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models

Based on our results it seems that GSH depletion and ROS production is important factors in rotenone induced cytotoxicity in the two fish gill cell lines, and the differences reflect their different sensitivity towards rotenone induced cell death

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The grading system that we used to assess small bowel image quality is described in Table 1