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3 Overview of NLRP3 inflammasome Innate immunity serves as the hosts primary defense barrier, wherein pattern recognition receptors (PRRs) on immune cells detect pathogen-associated molecular patterns (PAMPs), such as viral nucleic acids, bacterial lipopolysaccharides, and flagellin, or endogenous DAMPs released from damaged or dying cells
Giljohann DA, Seferos DS, Daniel WL, Massich MD, Patel PC, Mirkin CA
these changes showed up by week 3 and held at 2 months
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