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Leistikow et al

Coverage is typically more feasible when prescriptions are tied to FDA-approved indications such as type 2 diabetes, obstructive sleep apnea, or obesity

Doctors rely on large-scale studies to feel confident about a drugs safety, and observational reports alone arent considered enough to give a full answer

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In humans, OCT1 is mainly expressed in the sinusoid membrane of hepatocytes, whereas in rodents, OCT1 is strongly expressed in the basolateral membrane of renal proximal tubule cells