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Choose the Right Form Cyanocobalamin : Most common but more likely to cause reactions

Prentki, M., Matschinsky, F

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A randomized, double-blind, placebo-controlled trial in 153 older adults taking the antidepressant citalopram found daily supplementation with 500 g vitamin B 12 , 2 mg of folic acid, and 25 mg of vitamin B6 for one year did not reduce the severity of depressive symptoms but increased the response to drug treatment and helped to prevent symptom relapse (112), suggesting B-vitamin supplementation might provide some benefit as an adjunct therapy

Daily 1,000 mcg Dosing in the Initial Phase In the first one to two weeks, daily injections of 1,000 mcg are given