Important safety information : Semaglutide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
For unopened Wegovy: Each single-use pen can be kept at temperatures below 30C (86F) for a maximum of 28 days Protection from light remains essential during this period For opened multi-use Wegovy pens: The pen cap must remain on when not in use to protect from light You can store for 8 weeks at temperatures below 30C (86F) or in a refrigerator (2C 8C) This significantly shorter room temperature timeline for unopened pens makes Wegovy somewhat less flexible than Ozempic for travel or storage without refrigeration
While the medication alone has a low risk of hypoglycemia, combining it with other glucose-lowering agents can raise concerns
The bioavailability of the tablet is 0.8% which is examined as lesser than injection
As a result, COX-2 inhibitors might contribute to cancer prevention or serve as adjunctive therapies
This includes other CNS stimulants, such as lisdexamfetamine (Vyvanse), and nonstimulants, such as atomoxetine (Strattera)