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Tan M, Li S, Swaroop M, Guan K, Oberley LW, Sun Y

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Other dendritic cells in the oral mucosa are the Langerhans' cells which are antigen presenting cells of the immune system, usually distributed in the superficial epithelium and are demonstrated on immunohistochemistry by S-100 or CD1a

Its important to inquire about underlying causes of gut dysfunction such as poor diet, medication use (eg, antibiotics, nonsteroidal anti-inflammatory medications, proton pump inhibitors, antacids, etc), an excessively clean and hygienic environment, psychological stress, and environmental toxins