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Behavioral and dietary interventions for weight loss are known to improve psychological well-being, including self-esteem, body image, health-related quality of life, and mental health, suggesting weight loss with GLP-1s may have similar beneficial impacts
Off-label use is when healthcare professionals prescribe a drug for purposes other than what the Food and Drug Administration (FDA) approved it to treat
In addition to their effects on appetite, GLPs also appear to impact the brains reward system, which plays a crucial role in craving and addictive behaviors
doi:10.1056/NEJMoa2301972 Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, O'Farrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z