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After anti-aging treatments (e.g

Interestingly, Lira has also been shown to attenuate negative feedback inhibition of bile acids by inhibiting intestinal FXR activity and ultimately reduce bile acid synthesis in the liver [76]

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Overall these alterations in metabolism pathways resulted in a substantial reduction in the levels of metabolites such as aspartate, asparagine, glutamine, histidine, N-formimino-glutamate, sarcosine, and ethanolamine phosphate in LC patients ( Figure 4B , Supplementary Figure 3B )