The compound is a synthetic pentadecapeptide originally identified through analysis of naturally occurring gastric peptides
Most research-based protocols suggest starting at a conservative dose and titrating based on individual tolerance and response
Notably, in animal (rodent) models of schizophrenia and autism, maternal infection with the H1N1 virus results in prenatal alterations in the genes of the offspring which include changes to GRIK2 and GABAergic genes leading to structural changes in the brain and adverse effects on behaviour (Hossein Fatemi, Powerpoint presentation, 2011)
Laranjo, M
The importance of GST A3-3 is shown by inhibiting the enzyme with drugs or by RNA interference of GST A3-3 biosynthesis, treatments which both suppress the hormone production in two steroidogenic human cell lines ( Further evidence for the physiological relevance of the GST isomerase activity derives from the coregulation of dehydrogenase and GSTA3 gene transcription in the horse ( Future Prospects The available data suggest that GSTs have a supportive function, which can prevent the overproduction of the 3-keto delta5-steroids formed by hydroxysteroid dehydrogenases and thereby prevent product inhibition
The therapy is often used to support specific health goals, and it is important to consult with your healthcare provider for guidance