Hepatic (liver-related) causes The liver is a major reservoir for cobalamin, so liver disease is one of the more common explanations for a high B12
For instance, a review we conducted at this time of ClinicalTrials.gov.org using NAD + as other term input and the following precursors as intervention reveals that there are 4 clinical trials investigating NA, 7 trials focused on NAM, 8 trials administering NAD + , 16 trials studying NMN, and over 60 trials exploring NR with NAD + measurements included as readout
Important note: human safe dosing has not been established for any of these compounds
Are there any known downsides when comparing GHK-Cu vs KLOW
Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG
It is typically a progressive waxing and waning process that may deteriorate over years