Both approaches effectively support glutathione status through different mechanisms.* Why might NAC be preferred over direct glutathione supplementation
There's good support for patience here: time to therapeutic effect remains similar at roughly 8 to 12 weeks regardless of escalation speed, so patients don't sacrifice their treatment timeline by following gradual protocols
ER structure and function
however, the clinical significance and durability of these effects remain under investigation
Annu Rev Biomed Eng 4:261286 Ben-Hur T, Idelson M, Khaner H, Pera M, Reinhartz E, Itzik A, Reubinoff BE (2004) Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats
The corresponding graph is presented in figure 7