doi: 10.3390/antiox8090413 49 JainSKParsanathanRAchariAEKanikarla-MariePBocchiniJA
Flow cytometry and sorting For surface staining cells were incubated at 48 C, in the dark with fluorochrome-conjugated CD19, CD23, CD21-CD35 or CD35, IgD, IgM, CD1d, CD24, CD93, CD95, and GL-7 diluted 1:200 (refer to Supplementary Data 4 for details)
A Phase 2 trial by Metabolic Pharmaceuticals found that while the compound was well-tolerated, it did not produce statistically significant weight loss versus placebo at the doses tested
In cultured dermal fibroblasts, assays quantify pro-collagen I/III and matrix metalloproteinases (MMP-1, MMP-9) alongside their inhibitors (TIMPs)
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