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The acquisition was performed using a BD FACSAria III SORP cell sorter (100 m nozzle) and analyzed using FlowJo software v10.10.0 (FlowJo LLC)

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Male rats, oral LD50: 4900 mg/kg

All of Us cohort enables first POAG GWAS for individuals of Admixed American/Latino ancestry The modest sample size of the Admixed American/Latino population in our cohort (465 POAG cases, 67,875 controls) has enabled us to conduct an ancestry-specific GWAS for this demographic, whereas previous studies suffered from small sample size and thus were only powered to perform cross-ancestry meta-analysis 28