Within the pancreas, proglucagon undergoes a transformation into glucagon, glicentin-related pancreatic polypeptide (GRPP), and the main proglucagon fragment (MPGF)
Nature 562 , 217-222 (2018) PubMed
Diabetologia 16 , 7585 (1979)
Symptoms of dyspepsia, nausea, vomiting, bloating, diarrhea, and constipation stand out among the gastrointestinal adverse effects described.514 The presence of gastrointestinal adverse effects associated with antidiabetics has an overall impact on the patient with diabetes, given that they can increase the need for medical attention, affect quality of life due to the symptoms they trigger, and modify therapeutic regimens
Tracking Progress Beyond the Scale Weight isnt the only indicator of success
When GLP-1 RAs are not used concomitantly with a sulphonylurea or insulin, routine glucose monitoring is unnecessary due to the low risk of developing hypoglycemia