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In general, iron overload in cells, decreased GPX4 and xCT expression, activation of acylCoA synthetase long-chain family member-4 (ACSL4) and lysophosphatidylcholine acyltransferase-3, and an increase in lipid peroxidation are the four main mechanisms that induce ferroptosis [82,83,84]

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Prioritize Self-Care: Complement your treatment with activities like meditation, journaling, or yoga to reduce stress and enhance mental clarity

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Jun JS, Lee ST, Kim R, Chu K, Lee SK

In the bodys high-glucose state, due to changes in metabolic substrates, the oxidation of free fatty acids increases the transfer of reducing equivalents, which can damage the ability of the electron transport chain, increase the generation of reactive oxygen species, excessive reactive oxygen species deposition, or weaken the antioxidant mechanism