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Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study

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6.4.2.1 Drugs Metformin is a well-known AMPK activator: it phosphorylates AMPK at the T172 site, thus blocking the expression of matrix metalloproteinase-2 (MMP2) and MMP-9, which may be related to abnormal follicular atresia (165, 166)

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