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doi: 10.26355/eurrev_202009_23048 95 WengY

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An abundance of the microbial metabolite tryptophan has been observed in the gut of SLE patients and lupus-prone mice and is considered to shift the composition of the gut microbiome (123, 127, 128)

G6PD-d and IL-10 In several animal models of ASCVD, IL-10 has been shown to reduce plaque burden and improve plaque phenotype while ApoE-/- IL10-/- double knockout mice develop increased atherosclerosis 48