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The dose is gradually increased every 4 weeks: first to 0.5 mg, then 1.0 mg, then 1.7 mg, and finally to the target maintenance dose of 2.4 mg weekly for weight management

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Safety and Tolerability Both compounds share a dominant, mostly mild-to-moderate gastrointestinal adverse-event profile nausea, vomiting, diarrhea, constipation, abdominal pain concentrated during dose escalation

10.1016/j.ajp.2021.102896 79 RabbaniG